A newly revealed DHS memo shows the Trump administration explored using National Guard troops as immigration officers. Legal ...

CBS Sports analyst Tony Romo pleaded no contest to an OWI charge after his Milwaukee arrest, citing pain medication ...

The San Diego Padres are bringing in reinforcements for the stretch run with the promotion of top prospect Ethan Salas.

Jose De Jesus Anguiano offered money, marijuana and alcohol to four minors between the ages of 13 and 17 as part of attempts to coerce them into engaging in sexual acts with him, authorities said.

UC San Diego researchers have received an $11.3 million contract to develop "smart" red blood cells to give soldiers an ...

San Diego County Board of Supervisors honored the Jewish community and the upcoming High Holidays with a proclamation at ...

A pedestrian lost his life over the weekend to a late-night hit-and-run in Escondido, authorities reported Monday.

A controversial policing tactic that permitted staggering amounts of fentanyl to reach the streets as federal authorities ...

Tuesday marks the first day that San Diegans can hail a public ride in an autonomous Waymo vehicle. Waymo is expanding its ...

A homicide investigation is underway after a victim was found dead in Clairemont, according to the San Diego Police ...

The Monarch School has been temporarily closed, and students have been relocated over concerns about possible mold on campus.

Manny Machado had four hits, Michael King struck out six in six innings and the San Diego Padres defeated the Cincinnati Reds ...